Polygenic Risk Scores

Population-level estimates of disease or trait risk based on many small genetic effects.

Articles about Polygenic Risk Scores

Genetics
DNA Signals Predict Depression Risk

DNA Signals Predict Depression Risk
A massive new genetics study ties hundreds of tiny DNA differences to major depressive disorder, improving risk estimates and pointing to brain cell targets — but genetics alone w…
Science
Single Gene Linked to Mental Illness

Single Gene Linked to Mental Illness
Researchers report that loss-of-function variants in the GRIN2A gene can directly produce early-onset psychiatric illness, challenging the idea that major mental disorders are alw…